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Aldactone Feedback

If you've used Aldactone, please help others by adding your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.

Subj: Breathing problems
Date: 11/29/2008
Severe shallow breathing!!

AskDocWeb: As with any breathing problems, please call your doctor.

Subj: Concerned about cancer
Date: 10/21/2009
I've been taking 150mg. of aldactone for about 2 years now to treat hair loss. I recently read that this medication has been known to cause cancer in laboratory rats; so I would like to taper off of it. I am wondering how taper off properly?

AskDocWeb: That may depend on your current medical condition. Because this drug affects your potassium and hormone levels, you should discuss this with your doctor before discontinuing.

Subj: Increase of cellulite?
Date: 12/18/2010
does aldactone cause increase of cellulite? I was told that due to dehydration the body tends to store fat.

AskDocWeb: The product information for Aldactone (spironolactone) does not list an increase in cellulite from Aldactone use. There are several factors that influence the production of cellulite: heredity, lymphatic, intestinal, hormonal, circulatory, liver function, and lifestyle factors. The key to getting rid of cellulite and keeping it off is often found in restoring a healthy metabolism.

Subj: Conceived after taking aldactone
Date: 12/25/2010
I was taking aldactone 170 mg for 3 months for hairloss from post stopping oral pill. My last period was the day of my last dose of aldactone and then I got pregnant. For how long does the effect stay in the body as I must have concieved 2-3wks post stopping the the pill....plz help

AskDocWeb: Aldactone is a trade name for spironolactone, also sold as Aldactazide, Berlactone, Novo-Spiroton, Spiractin, Spirotone, and Verospiron. It has a relatively short half-life however it is metabolized into canrenoate, which has a longer half-life of 10 to 35 hours. After two weeks there would be somewhere between 0.13% and less than one-in-13-billionth of the original dose left. Unfortunately the hormonal effects stay around longer.

According to an article in Nurse Practitioner (2003;28:8-25), The pathogenesis and treatment of PCOS: "It is recommended that Spironolactone be discontinued 3 months prior to conception because of its association with menstrual irregularity and possible teratogenic effects." Please discuss this with your doctor.

Date: 4/13/2015
I had severe low potassium and was on 2 10meq 3 times daily. I was also on 2 lasix 20mg daily. I have multiple sclerosis and suffer from fatigue and severe muscle spasms and twitching. Thank you for your browser information. I now realize that the 20mg of spironolactone that the kidney Dr. Put me on is doing nothing but making me worse. Thank goodness Jesus helped me find it through you because these days the Drs. are so busy they didn't seem to concerned with my irregular heart beat and chest pain, back ache and kidney pain. Thank you so much.

AskDocWeb: Always talk to your doctor before discontinuing any prescription drug. When taking multiple drugs it is very important to check for interactions between those drugs.

Adverse event
Date: 11/11/2016
I would like to report an adverse event that occurred while taking Spironolactone and the antibiotic Metronidazole. I experienced a serious sudden drop in blood pressure. The diuretic was prescribed in August to treat high aldosterone levels. I also had elevated blood pressure for more than a year. Avg. 137 / 95. Highest reported 165 / 90 I started taking a daily dose of Spitronolactone 25 mg in August. An antibiotic Metronidazole 500 mg was prescribed during last week of September to treat an intestinal complaint (possible parasite). Dose was 500 mg three times a day.

On day five of ten, a sudden loss of wellness occurred with extreme fatigue and difficulty breathing. Blood pressure when recorded 30 minutes later was 99 / 80. Blood pressure remained below 120 for week following the antibiotics + diuretic. Then pressure bounced up to 150 / 81. Has since decreased to previous average of 137.

AskDocWeb: Thanks Adele. You can also report adverse events to the Federal government. You can read more about that here.

Dizzy/vertigo attacks?
Date: 5/20/2017
Ive been off & on spiro for a year for acne... Ive been very inconsistent with my dose. I was on 50mg then bumped up to twice a day. But most days I could only remember to take it once...sometimes twice. I noticed I was a bit more anxious while taking the medication. But my real concern was with dizziness. Could the medication be responsible for crazy dizzy/vertigo attacks? It happened a few times in the last year usually within hours after exercising. It scared me a lot! I wasnt sure if they were panic attacks but I felt so dizzy suddenly while driving I thought I was going to black out so Id pull off to side of the road to collect myself. Its happened twice in the last two weeks. So I recently decided to just go off the medication completely to see if it had any change...& again about a week after I stopped spironolactone I again had a dizzy spell within hours after exercise. Could the medication still be in my system? I know my dermatologist said it takes months to get in your system and months to get out? How long can the blood pressure lowering effects last? Ive been taking my blood pressure @ home and its been 90/50's...85/60...80/40's...104/65...112/70... How long do side effects last? I read dizziness is a side effect of the medication... but Im not sure if these dizzy atfacks are related to the medication or not. Going to my doctor for a full work up this week. But was wondering if these symptoms could in any way be related to the medication.

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