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Grape Seed Extract

Natural health supplements sometimes have unexpected side effects or interactions with medication that can lead to adverse reactions that are sometimes life threatening. The following is a list of cautions that you should be aware of before using Grape Seed Extract (Vitis vinifera). These are referred to as drug/herb interactions.

Warning 1 - Contraindications: Until more is known about the affect of grape seed extract on women who are pregnant or breastfeeding its use is not recommended.

Warning 2 - Antihypertensive drugs: People with high blood pressure should discuss the use of Grape Seed Extract with their doctor before using this supplement.

Used as a natural health remedy: Grape seed extract may be effective in relieving the following symptoms and conditions:
  • atherosclerosis (hardening of the arteries)
  • osteoarthritis (See other herbs for inflammation)
  • chronic venous insufficiency (when veins have problems sending blood from the legs back to the heart)
  • diabetic retinopathy (an eye problem caused by diabetes)
  • hair loss (alopecia)
  • poor circulation
  • reducing swelling (edema) after an injury or surgery
  • vascular fragility (weakness in small blood vessels)
  • wound healing

Grape seed extract is prepared from the seed of grapes. It is available in capsule and tablet forms. Grape seed extract contains antioxidants, which help prevent cell damage caused by free radicals (molecules that can damage cell function).

Grape seed oil is used to keep skin moist and protect it from the harmful UV rays of the sun.

Side Effects of Grape Seed Extract

When taken by mouth, grape seed extract is generally well tolerated by most people. In clinical trials it has been used safely for up to 8 weeks. The known side effects of using Grape Seed Extract include the following:
  1. dizziness
  2. dry scalp
  3. headache
  4. high blood pressure
  5. hives
  6. indigestion
  7. itchy scalp
  8. nausea
The possible interactions between grape seed extract and medicines and other supplements have not been carefully studied. Other side effects may also occur when using Grape Seed Extract. Use the form below to report your experience.

As with any herb, a serious allergic reaction is possible. Seek immediate medical attention if you notice any symptoms of a serious allergic reaction. These may include a rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

Return to the Herb List.

For questions and answers about the side effects of herbs see the Herb Forum

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This consumer advocate website is protected by copyright 2011 Askdocweb, Inc. All Rights Reserved. This is a layman's report on Grape Seed Extract and is not intended to replace discussions with a health care provider. Do not use the information on this forum as a substitute for your doctor's advice. Always consult your doctor before taking any drug and follow your doctor's directions. Source material: Food and Drug Administration, Medline, Physician's Desk Reference, and the largest community of people in the world, those who are concerned about side effects and healthcare.
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