Jimsonweed
Natural health supplements sometimes have unexpected side effects or interactions with medication that can lead to adverse reactions that are sometimes life threatening. The following is a list of cautions that you should be aware of before using Jimsonweed (Datura stramonium). These are referred to as drug/herb interactions.
Warning 1 - Amantadine: Jimsonweed increases antocholinergic effects.
Warning 2 - Antacids: decrease the action of Jimsonweed.
Warning 3 - MAOIs: Jimsonweed increases the anticholinergic effects of MAOIs. Experts recommend avoiding concurrent use.
Warning 4 - Phenothiazines: Jimsonweed decreases the action of phenothiazines.
Warning 5 - Tricyclic antidepressants: The use of jimsonweed with tricyclic antidepressants increases the anticholinergic effects.
Warning 6 - Toxic: Jimsonweed contains toxic tropane alkaloids, which have caused poisoning and death in humans and other animals. It is generally considered too toxic for medical applications nowadays.
Used as a natural health remedy: Jimsonweed has been used internally for:
- asthma
- cough
- epilepsy
- madness
- melancholy
There is very little data to support the therapeutic use of jimsonweed.
Side Effects of Jimsonweed
The known side effects of Jimsonweed include:
- Agitation
- Blurred vision
- Confusion
- Decreased GI tract motility
- Dilated pupils
- Dry mouth
- Dry mucous membranes
- Dry, flushed skin
- Emotional lability
- Headache
- Hypertension leading to hypotension
- Hyperthermia
- Intensely negative hallucinations
- Loss of consciousness
- Motor incoordination
- Nausea
- Photophobia
- Restlessness
- Tachycardia
- Tachypnea
- Urinary retention
- Vomiting
Jimsonweed is listed as an unsafe herb by FDA and is not recommended for routine therapeutic use.
As with any herb, a serious allergic reaction is possible. Seek immediate medical attention if you notice any symptoms of a serious allergic reaction. These may include a rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
Return to the Herb List.
For questions and answers about the side effects of herbs see the Herb Forum
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