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MelatoninNatural health supplements sometimes have unexpected side effects or interactions with medication that can lead to adverse reactions that are sometimes life threatening. The following is a list of cautions that you should be aware of before using Melatonin (known chemically as N-acetyl-5-methoxytryptamine ). These are referred to as drug/herb interactions.
Warning 1 - Contraindications: Pregnancy and lactation (breast-feeding)
Warning 2 - Benzodiazepines: Melatonin may increase the anxiolytic or anxiety relieving effects of benzodiazepines, use cautiously.
Warning 3 - DHEA: Melatonin may decrease cytokine production, the proteins that serve to regulate the immune system. Experts recommend avoiding concurrent use.
Warning 4 - Magnesium: Using Melatonin while taking magnesium supplements increases inhibition of NMDA (N-methyl-D-aspartate) receptors in the brain. These receptors play a part in memory and your ability to learn new things. Experts recommend avoiding concurrent use.
Warning 5 - Zinc: Using Melatonin while taking a zinc supplement increases inhibition of NMDA (N-methyl-D-aspartate) receptors in the brain. These receptors play a part in memory and your ability to learn new things. Experts recommend avoiding concurrent use.
Warning 6 - Orthostatic intolerance: Using Melatonin may exacerbate symptoms by reducing nerve activity in those with orthostatic intolerance.
Warning 7 - Auto-immune disorders: Melatonin supplementation may exacerbate symptoms due to immunomodulation.
Warning 8 - Succinylcholine: This herb increases the blocking properties of succinylcholine. Experts recommend avoiding concurrent use.
Warning 9 - Drug interactions: There is some evidence to suggest that melatonin may interact with various medications, including, blood-thinning medications (anticoagulants), immunosuppressants, diabetes medications, cerebral stimulants, and birth control pills.
Used as a natural health remedy: melatonin is used internally for these benefits:
Side Effects of MelatoninThere are no major or severe side effects with this supplement. However, side effects may show up when using Melatonin at high doses. These include:
As with any herb, a serious allergic reaction is possible. Seek immediate medical attention if you notice any symptoms of a serious allergic reaction. These may include a rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.Return to the Herb List.
For questions and answers about the side effects of herbs see the Herb Forum
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This consumer advocate website is protected by copyright © 2011 Askdocweb, Inc. All Rights Reserved. This is a layman's report on Melatonin and is not intended to replace discussions with a health care provider. Do not use the information on this forum as a substitute for your doctor's advice. Always consult your doctor before taking any drug and follow your doctor's directions. Source material: Food and Drug Administration, Medline, Physician's Desk Reference, and the largest community of people in the world, those who are concerned about side effects and healthcare.