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Nexium Side Effects

If you've used Nexium, please help others by sharing your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.

Subj: Severe joint pains
Date: 11/10/2009
I was using Nexium but had to stop because of the severe joint related pains. It started with my shoulders then finger joints & then ribs. It got to the point where it was painful to deep breathe. The period I took Nexium was 4 moths. A pharmacist told me Nexium leached minerals from the body. I still have residual aching in my right hand & shoulders, like arthritis.

Subj: Nexium and fertility
Date: 11/12/2009
I am 29 years and taking Ulcer treatment for the past 2 years, did gastroscopy and my stomach layer was really really bad. I was given nexium for the first 6 months and was still not ok, and my doctor put me on the Topzole and now I'm on Nexium for the last Six month till February. Is this a bad thing that I'm taking this medication as I don't have kids yet and I sometimes worry if I won't have problem having kids or falling pregnant after taking this medication for years.

AskDocWeb: The only effects listed for Nexium on the reproductive system are dysmenorrhea (menstrual pain), menstrual disorder, and vaginitis (vaginal inflammation). There is no mention of any affect on fertility.

Subj: Nexioum
Date: 11/13/2009
If you dont take Nexioum dont start! It will ruin your GI tract!

Subj: Tolerance to Nexium?
Date: 11/19/2009
Can someone build a tolerance to Nexium? I've been taking it for about 1 1/2 years and seem to be getting some symptoms I use to get...burbing, sore throat, etc...I am taking 20 mg....maybe I need 40 mg now.

AskDocWeb: People do not seem to develop a tolerance to PPIs (including Nexium) as they can with H2-receptor antagonists. However, it is possible that your condition has changed and you may need to revisit your doctor for something new.

Subj: Weight gain 40 lbs
Date: 11/19/2009
Have been using Nexium for years. Weight gain 40 lbs. I terrified this will continue. Also have discovered that I have hypothyroid. Any connection between the two? What are the alternatives to Nexium? If I get off of it, will weight stabilize? Thanks so much.

AskDocWeb: We found no connection between Nexium and hypothyroid. If you are looking for treatments for GERD (GastroEsophageal Reflux Disease) the alternatives include Aciphex, Axid, Pepcid, Prevacid, Prilosec, Protonix, Tagamet, Zantac, and Zegerid. Don't stop taking Nexium without first talking to your doctor.

Subj: Mixed results
Date: 11/19/2009
I've been on Nexium for over a year and even though it did help I started having other problems. I have chest pain, some edema in my legs, numb and tingling fingertips, and I have put on 20lbs. I just stopped taking it because the problems just keep coming. Now I have vitamin D deficiency. I went back on Prilosec and will see how that works for now.

Subj: Sinusitus, headache, earache and sore throat
Date: 11/20/2009
Hi, I have been on Nexium 20mg daily for last month, I have developed sore sinusitus, headache, earache and sore throat, as well as constant heartburn that does not seem to be relieved with drugs. Is the sinusitis etc symptoms of Nexium or just that I have not controlled my reflux symptoms- Do you think would be better on different drug or my dosage needs to be increased?

AskDocWeb: It does sound like you should check back with your doctor. Sinusitis and headache are listed as possible side effects of Nexium. A sore throat is not listed as a side effect but Nexium could cause bronchospasm. That is an abnormal contraction of the bronchi, which results in narrowing and blockage of the airway. Bronchospasm is the main characteristic of asthma and bronchitis.

Note that some sinusitis-like symptoms are caused by a special kind of acid reflux called laryngopharyngeal reflux (LPR). Nexium has been reported to be helpful for this condition.

Subj: Best time to take Nexium?
Date: 11/20/2009
My doctor says Nexium needs to be taken in the morning before breakfast, with an empty stomac. Otherwise, it will not work for all three meals of the day. Is this true? What if I would rather take it in the evening, either before dinner or before going to bed, also with empty stomac?

AskDocWeb: One dose is intended to provide relief through three meals. For example, if you took it before the evening meal, say at 5:00PM. 19 hours would pass before lunch the next day. Compare that to taking your daily dose before breakfast, say 6:00AM. In this case 12 hours would pass until the evening meal. Since the effects of the drug wear off over time, you can understand why your doctor wants you to take it in the morning.

Subj: Short term memory loss
Date: 11/22/2009
I have been taking Nexium now for (5) years due to being diagnosed with GERD. I have had the scopes in both ends and the first impression by the doctor was that I had Barretts, but the tests came back negative. I've tried to get off the Nexium, but each time I do, I begin having severe pain in the center of my chest with each breath. The only thing that helps is the Nexium but I don't know how long I should be taking it, as it seems like every other person is able to get off it after a brief time. Secondly, I have noticed an abrupt loss of memory for things (like short term memory loss), could this be from taking the Nexium for an extended period of time?

AskDocWeb: That is possible, memory loss is listed as a side effect of Nexium with an occurance rate of less than 1%. However, when you multiply that by millions of consumers that means tens of thousands of people share this problem.

Subj: Major joint pain
Date: 11/24/2009
I have been taking Nexium for the past 3 months for GERD. Lately, I have been suffering from major joint pain, throughout my entire body. Could Nexium cause this and should I stop the medication for a while? Is it safe to abruptly stop Nexium?

AskDocWeb: Joint pain is one of the possible side effects of Nexium but talk to your doctor before stopping use.

Subj: Very bad headaches
Date: 11/25/2009
I have been on nexium for a couple months now and I have very bad headaches. I have never had headaches before now every time my blood pressure goes up I get sever migranes. This only started shortly after taking nexium.

Subj: I called the FDA
Date: 11/29/2009
I was on Nexium for about 10 years, About 2 years ago I started having trouble with my blood pressure. It was 190/110. I was put on high blood pressure meds. I was having all kinds of problems like feeling like I was going to pass out to be very ill in my stomach to explosive bowel movements. I told my doctor and I was told it was not the Nexium. It got so bad I swear I was going to die. I stopped taking the Nexium about 2 months ago and my blood pressure went back to normal 120/80. I told the doctor and still was not believed. I called the FDA and told them what had happened and I was told that Nexium can cause High Blood Pressure. Please make sure you discuss any changes in your BP with your doctor. Since I stopped taking Nexium I no longer have the sick spells.

Subj: No more drugs for me!
Date: 12/1/2009
I gained 15 lbs while taking nexium. No matter what I did the weight kept going up. I also had IBS while taking it. I stopped taking it 3 weeks ago and the IBS is gone and I've lost 7 lbs. I'm going the natural route. Eat healthy and exercise. No more drugs for me!

Subj: Nexium for asthma?
Date: 12/1/2009
I have been taking Nexium for about one week and my doc prescribe it for me coz I had asthma and my doc said that the asthma is b/c of Regurgitation so I take Nexium for Regurgitation, but I dont feel that I have Regurgitation, but I want to ask if its ok to take it with singulair and loratadine and what would happen if I dont have Regurgitation? Thnx,

AskDocWeb: The exact cause of asthma is still unknown, although many of the things that trigger attacks have been identified. When an asthma attack occurs, the bronchial tubes or breathing airways become narrow, or even blocked. As a result air can't get in and out of the lungs easily and breathing becomes more of an effort. Two reasons have been identified for the narrowing of the bronchial tubes. Either they are squeezed by muscles from the outside or they are blocked by mucus and swelling on the inside of the tubes. When the narrowing of bronchial tubes is caused by muscle contractions, the condition is called bronchoconstriction. For many years this was thought to be the main cause of asthma. More recently bronchial inflammation has also been identified as a major cause. It is normal for your bronchial airways to produce some mucus in order to trap irritants when inhaling which protects the lungs. But some asthmatics produce an overabundance of mucus and the bronchial tubes can become inflamed, resulting in blocked airways.

Because many asthma patients also have acid reflux it appeared that there was a link between stomach acid that backs up into the esophagus (your regurgitation) and asthma. The theory was that as you breathe in during reflux, stomach acid was inhaled into the lungs, which then caused the asthma. News of a new study in the April 9th issue of the New England Journal of Medicine shows that theory will have to be reevaluated, if not dropped. The results of that study found that the rate of asthma events in the control group (not treated) was 2.3 per person-year and 2.5 events per person-year in those treated with a Nexium. The study was conducted by the American Lung Association's Asthma Clinical Research Centers at 20 sites across the United States. This was the most extensive study to date on the effectiveness of using heartburn medication to treat asthma symptoms. According to Dr. Elizabeth Nabel, director of the National Heart Lung and Blood Institute, which helped pay for the study, "Asthma patients who take medication for acid reflux but who do not have reflux symptoms should talk with their doctors about whether they should continue the medication."

Subj: Don't know what to do
Date: 12/1/2009
I have been taking nexium 40mg for about a year now. For a while I felt great and had alot of energy. But now I have no energy and I am having abdominal pain and constipation. Very bad. I only eat about twice a day and I have no desire to eat. Small meals. I have stop eating junk food to see if I felt better and I have not still. I just fell lifeless. And I feel like I cant breath all the time. My gerd doctor told me I had chronic reflux. I belch all the time and seems like I cant stop. He also told me I had a h. hernia. I use to weigh 170 and now I'm down to 138. I dont know what to do.

AskDocWeb: If you are not satisfied with your level of progress you can ask your doctor for a referral to a specialist.

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This website is protected by copyright 2007-2009 Askdocweb, Inc. All Rights Reserved. This is a layman's report on Nexium and is not intended to replace discussions with a health care provider. Do not use the information on this forum as a substitute for your doctor's advice. Always consult your doctor before taking any drug and follow your doctor's directions. Source material: Food and Drug Administration, Medline, Physician's Desk Reference, and the largest community of people in the world, those who are concerned about side effects and healthcare.
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