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Nexium Side Effects

If you've used Nexium, please help others by sharing your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.

Subj: Long term effects
Date: 4/21/2010
My husband has been taking Nexium for the past year. We were concerned about the long term effects of taking this drug on a daily basis. One of the things we found out through our own research is that the lack of acid prevents the body from absorbing calcium in the diet. (Hip fractures) Calcium needs an acid to absorb. Calcium citrate is most easily absorbed calcium. Also Nexium users should take digestive enzymes (health food store) with each meal to properly digest their food. Stool floaters have undigested fat - this is why they float. Hope this helps other Nexium users.

Subj: Lung and vocal cord problems
Date: 4/22/2010
Have been on Nexium for 6 months due to GERD and acid that aspirated into my lungs, causing continuous lung problems, and vocal cord problems. Nexium helps, but I have a ongoing "bruised" feeling just below my breastbone in the middle and also to the right (where galbladder used to be). It gets painfull occassionally and I am concerned.

Subj: Diagnosed with GERD
Date: 4/23/2010
My husband has been on nexium for quite awhile. He has not been diagnosed with GERD. I would like him on something like malox if needed. The cost of nexium is huge. Thanks.

AskDocWeb: Since he has been using Nexium for quite awhile, maybe it is time to reevaluate his condition to find out if he still needs it or not.

Subj: Cortisone?
Date: 4/24/2010
Does Nexium contain cortisone?

AskDocWeb: No, there is no cortisone in Nexium. The active ingredient in Nexium is esomeprazole. The inactive ingredients are glyceryl monostearate 40-55, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer type C, polysorbate 80, sugar spheres, talc, and triethyl citrate. The capsules containing the Nexium (shells) are made of the following inactive ingredients: gelatin, FD&C Blue #1, FD&C Red #40, D&C Red #28, titanium dioxide, shellac, ethyl alcohol, isopropyl alcohol, n-butyl alcohol, propylene glycol, sodium hydroxide, polyvinyl pyrrolidone, and D&C Yellow #10.

Subj: Low white blood cell count
Date: 4/27/2010
Is it possible to experience a low white blood cell count when on Nexium for a long time? I have been on it for many years. My Endo doc looked it up and low white blood cell count was a side effect. Will it get worse as time goes on. I can't stop taking Nexium and I have Barrett's, a Hernia and when I miss a pill, instant heartburn. Also, does Nexium increase the appetite? And for carbs?

AskDocWeb: According to Astra-Zeneca Pharmaceuticals (the manufacturer of Nexium), low counts of all blood cells including red and white blood cells, and platelets were reported in one percent or less of patients using Nexium. An increase was also seen in these factors in one percent or less of those using Nexium. An increase of appetite is listed as possibly or probably related to Nexium with an incidence rate of less than one percent.

Subj: Flu like symptoms
Date: 4/29/2010
I have Barretts and have been on nexium or simular drugs for over 10 years. Since taking these I go through periods that when I eat I have flu like symptoms - achy, etc. I have told this to my various doctors and they are perplexed and have no answer. My gall bladder seems to have polips but no stones. Carafate helps sometimes but not always. During these times certain foods really trigger the symptoms like greasy or soft drinks. Help!
Ben (the lawyer)

AskDocWeb: It is helpful to learn to recognize (and avoid) as many triggers as possible. Flu-like disorder is listed as one of the possible side effects of Nexium that occurs in less than one percent of patients.

Subj: Overwhelming side effects
Date: 4/29/2010
22-year-old male. I stopped taking Nexium after using 40 mg twice per day for 4 years. The side effects started to become overwhelming (adult onset lactose intolerance, nausea, bloating, constipation, diarrhea). The "acid rebound" was manageable with help from Pepcid and aloe vera juice, and only lasted a week. After I stopped, I felt a lot better for about 2 weeks. Now my side effects are as bad as ever, even worse than when I was on Nexium. Bloating and nausea after meals, irregular, painful, and loose stools. Severe anxiety. Excessive thirst and frequent urination. By using Nexium for so long have I totally wrecked my digestive system? Will these side effects last forever? I am planning to turn to natural relief like digestive enzymes and probiotics, it seems like my only hope.

AskDocWeb: Sometimes it is difficult to tell the difference between the side effects caused by a medication and the symptoms of a disease or condition. You may need the help of a specialist to sort it out. If GERD (gastroesophageal reflux) is left untreated, it may cause permanent damage to your stomach, esophagus, throat and/or larynx. There are no reports that Nexium may cause any permanent damage.

For readers who are considering the use of Aloe Vera, be sure to check for side effects and cautions.

Subj: Rectal symptoms
Date: 4/30/2010
Taken nexium for 2 months and aciphex for 4 months. endo-grade2 esophagitis and mild gastritis symp controlled very well. Developed new symptoms like muscle pain-back, leg muscle twitching-abdomin, thigh, perineum. 1 month after starting drug got anorectal burning, pain spreading to lower abdomin and privates-relieved by anovate cream. Then there was bright red blood, told was fissure. Had bleeding about 5 times in 4 months. Took calcium dobesilate(6d), sitz bath and high fibre diet(till now), anorectal burning discomfort on and off, discomfort in hip region relieved by passing stools-looks undigested.

QUEST-1. Will ppis cause rectal discomft, bleeding, cyclic(1.5mnths) colitis type diarrhoe? Reason; when I stop the drug I dont have rectal burning or discomrt.

2. I once tapered to twice a week for 3wks and stopped-after 10 days I got nausea, dizziness, bitter taste, weakness, burning in abdomin and chest diarrhoea, in this period no rectal symptoms. I had to take again 1/d for 10 days, alternate days for 3 wks. Now once in three days for past 2wks. again I am feeling week, diarrhoea 1day, again no rectal symptoms for past 4 days. My gastro is telling to do colonoscopy, dismisses nexium has to do anything with the rectal sympt. ???

AskDocWeb: Although abdominal pain and diarrhea are listed as possible side effects of Nexium rectal discomfort is not on the list. Sometimes a colonoscopy is necessary in order to find out what is going on in there.

Subj: Stopped taking nexium
Date: 4/30/2010
Very helpful information...I stopped taking nexium after two mos. 30mg daily due to extreme fatigue, muscle and bone pain and all my teeth hurt...The pharmacist said I fell into the 1% who have problems...I had taken nexium several yrs ago and experienced tingling and numbnes then pain in my hands and feet...I also experienced teriffic gas in my chest at times...It was interesting to learn that the gastric upsrt can act up when you go off the medication...that's helpful...also I will try the cider vinegar cure...I have the 6inch blocks for the bed on order from amazon and hope that will help...I miss chocolate.

Subj: GERD
Date: 5/1/2010
I started taking Nexium 2 years ago after a diagnosis of hiatus hernia, oesophagal restrictions and GERD. I have only just realised the side effects I have developed. I have swollen legs, gained about 20lbs, have swollen painful joints and sleeplessnes. After reading this site I am now convinced that I am goinbg to move to homeopathy.

AskDocWeb: Please discuss any change in treatment with your doctor. If GERD is not treated, it may cause permanent damage to your stomach, esophagus, throat and/or larynx.

Subj: Weight gain
Date: 5/3/2010
Hello I have been on nexium 40mg for like 6 yrs now & since I have gone from 47kg to 80kg with no changes in my diet at all, could this be the reason for it?

AskDocWeb: It is possible, both weight gain and weight loss are reported by less than one percent of those using Nexium.

Subj: Esophagitis
Date: 5/6/2010
I have had mild reflux problems for years, but now have been quite sick and diagnosed with oesophagitis. I have been on Nexium 40mg for a couple of months and have cut down to 20mg and it has been working well but I have just recently realised that since I have been on it I have had itching (I thought it was just the hot weather) and am now losing quite a lot of hair. I would like to get off the Nexium and have tried to stop taking it. I stopped for about 4 days (all my itching went away) but my stomach eventually got too upset so I am going to see if I can be changed to a different medication. I would like to know if I lose some more weight (I have already lost 7kg) do you think I would be able to do without the medication or is this a permanent problem that once you have it, it will not go away.

AskDocWeb: That depends on the type of esophagitis and extent of the damage. Has your doctor used an upper GI endoscopy to evaluate your condition as well as exclude such things as Barrett's esophagus?

Subj: Take these forever?
Date: 5/6/2010
I have been taking nexium for over 2 years now and has worked excelent for me but i want to know will i have to take these for ever now as when i don't take one for one day i can't digest food again are they harmfull over a long period at all.

AskDocWeb: Typically lifestyle modifications must be followed lifelong, because this is generally believed to be an irreversible condition.

Subj: Surgery didn't help
Date: 5/8/2010
I was born with reflux on my thirties Dr operated a Vagotomy, Hiatus hernia and duodenum ulcer was done all at once but still reflux, Nexium has been great for many years but now I have unexplained low back, hips and leg pain. Specialist can not find the cause low back and hips, bone OK; (MRI normal} I last only two days with out Nexium.

AskDocWeb: Long term follow-up studies have revealed that 52% of patients that undergo anti-reflux surgery start taking anti-reflux medication again within 3 to 5 years. There is still a much about the symptoms that accompany GERD that are poorly understood and in many cases no clear cause is found.

Subj: Is it safe
Date: 5/9/2010
I have been taking Nexium 40mg since 2004. My family practitioner felt I should not have to continue. Lately I missed a dose with no affects. I have been off Nexium for about five days now with still no heartburt or reflux. I am planning on seeing a specialist, but in the mean time is it safe to continue what I am doing?

AskDocWeb: Typically the safest course of action is to follow your doctor's instructions. A family doctor is good for many health issues but sometimes you need a specialist to zero in on the exact cause of a problem.

Read more feedback about Nexium.

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This website is protected by copyright 2007-2010 Askdocweb, Inc. All Rights Reserved. This is a layman's report on Nexium and is not intended to replace discussions with a health care provider. Do not use the information on this forum as a substitute for your doctor's advice. Always consult your doctor before taking any drug and follow your doctor's directions. Source material: Food and Drug Administration, Medline, Physician's Desk Reference, and the largest community of people in the world, those who are concerned about side effects and healthcare.
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