Propecia Reviews

• AndroScience Corp. is working on a drug that directly affects hair follicles by reducing their ability to absorb dihydrotestosterone (DHT), the hormone that stops hair growth.
• Hopefully Pfizer will come out with one of the products they are working on. One is a drug that works the same way as Rogaine and the other is a drug treatment that mimics the effect of thyroid hormones on hair growth.
• Hair transplants are about to get faster and cheaper if the new surgical equipment under development by Restoration Robotics works out.
• Follica Inc. is in the early stages of developing new methods for growing new hair follicles.
• Copper peptides are still being researched because they shorten the resting phase of hair follicles, resulting in more hair follicles on the scalp being in the growing phase (as opposed to the resting or falling out phase) at one time. Nanogen, a UK-based skin research company, is undergoing Phase I trials to assess the potential of hair regrowth of a new "broad-spectrum" molecule which is copper II based. The company has not released details on the molecule because it is still pending a patent.
• New research from Rockefeller University has revealed that the structure at the base of each strand of hair, the hair follicle, uses a two-step mechanism to activate its stem cells and order them to divide. The self-renewal process of stem cells in the hair follicle appears to control the life cycle of hair growth. For a new round of hair growth to begin, stem cells in the hair follicle must receive a signal to divide. In response to this signal, the hair follicle regenerates first by growing downward through the skin's middle layer and then produces the specialized cells that form the new hair. After a period during which the hair grows longer, stem cells stop dividing and the hair follicle gradually retracts again. There is then a period of rest and the cycle repeats.
• Hair cloning is getting closer as stem cells and dermal papilla cells have been discovered in hair follicles. Research on these cells is now known as hair multiplication (HM) and is being developed by two independent companies: ARI (Aderans Research Institute, a Japanese owned company in the USA) and Intercytex, a company in Manchester (UK).
  
  In 2008, Intercytex announced positive results of a Phase II trial for a form of cloning hair follicles from the back of the neck, multiplying them and then reimplanting the cells into the scalp. The initial testing resulted in at least two thirds of male patients regrowing hair. It appears that they are ready for Phase III trials.
• Aderans Research Institute is looking at ways to multiply certain cells from the scalp, which would then be injected or seeded into the scalp to generate new follicles.
• In May 2007, U.S. company Follica Inc, announced they have licensed technology from the University of Pennsylvania which can regenerate hair follicles by reawakening genes which were once active only in the embryo stage of human development. Skin apparently can be brought back to this embryonic state when a wound is healing. Hair growth was discovered in the skin wounds of mice when Wnt proteins were introduced to the site. Development of a human treatment is expected to take several years.
• In February 2008 researchers at the University of Bonn announced they have found the genetic basis of two distinct forms of inherited hair loss, opening up the possibility of a new range of products to treat hair loss. They found that a gene, P2RY5, causes a rare, inherited form of hair loss called Hypotrichosis simplex. It is the first receptor in humans known to play a role in hair growth. The fact that any receptor plays a specific role in hair growth was previously unknown to scientists and with this new discovery there is a focus on finding more of these. In May 2009, researchers in Japan identified a gene, Sox21, that appears to be responsible for hair loss in people.
• Researchers at GlaxoSmithKline and the Jewish General Hospital have identified two previously unknown genetic variants on chromosome 20 that substantially increase the risk of male pattern baldness. It's long been recognized that that there are several genes responsible for causing male pattern baldness. Until now, no one could identify those other genes. If you have both the risk variants on chromosome 20 and the unrelated known variant on the X chromosome, your risk of becoming bald increases sevenfold. About one in seven men have both of those risk variants. That's 14% of the total population. This discovery may lead to new products that are far more effective for treating hair loss.
• Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair. The enzyme is acyl CoA:diacylglycerol acyltransferase 1 or DGAT1. When researchers used genetic engineering to delete this enzyme in mice, they found that lack of DGAT1 caused hair loss. Their findings were reported in The Journal of Biological Chemistry.
• Other products under research to slow down hair loss are zinc, silica, pyridine N-oxides, methylsulphonylmethane (MSM), cod-liver oil and certain unsaturated fatty acids such as gamma linolenic acid.

• Provillus
• Nisim Biofactors (hair loss shampoo)