Feedback on Celebrex Side Effects and Usage from Users, page 15

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If you’ve used Celebrex, please help others by adding your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history. You can use the form below to add your comments, feedback or Celebrex review.

Subj: Flu like symptoms
Date: 9/29/2008
I had exactly the same experience as those described below. Also I have had flu like symptoms when I quit for only three days.

Subj: Flu like symptoms Date: 7/31/2005 I have been taking 100mg a day Celebrex for 2 months, since Mobic was taken off the market. Before that I was taking Vioxx for back pain and arthritis. My Dr. has suggested that I try Melrose Fish Oil to help with the pain. I found that this did help, and when I ran out of Celebrex I used only the fish oil. I found that I was very stiff and sore initially, but in the second week off Celebrex I developed what I thought was a virus – flu like symptoms for a week – feeling better today. Could this be a reaction to coming off Celebrex? Barbara AskDocWeb: It sounds like you may have had a bug.


AskDocWeb: In the post you referenced the flu like symptoms appeared in the second week following discontinuing Celebrex. If the flu like symptoms were connected to discontinuing a drug they would have shown up within 24 to 36 hours, not two weeks later.

Subj: Tired, achy, and foggy
Date: 10/7/2008
I was prescribed Vicodin for a week-long headache (while waiting to see a neurologist). The vicodin made me extremely ill, so the doctor prescribed Celebrex. I have been on it for about 4 days and at first I didn’t notice much of a difference. Now, after about 11 hours or so I feel awful!! Worse than before. Tired, achy, foggy. Is this because of the Celebrex or do you think my symptoms have elevated and I was not aware because of the pain medecine?


AskDocWeb: Please contact your doctor as sluggishness and drowsiness are signs of an overdose.

Subj: Stomach cramps and blood in stool
Date: 10/11/2008
I was given celebrex after telling my doctor that I was having chest pain which I thought might be due to a hernia that I was diagnosed with 6 years ago. I took the Celebrex 200 mg for a week when I started having severe stomach cramps and blood in my stool. I was told to stop the medicine, but 5 days later I am still having bloody stools which are very fiborous and very little stool. Should I be overly concerned or is this the medicine leaving my system?


AskDocWeb: The medication only takes a couple of days to leave your system so you should discuss this with your doctor.

Subj: A LOT of weight gain
Date: 10/15/2008
I am only 21 years old and very athletic. My doctor prescribed celebrex because I was constantly in severe pain in my joints and bones and tendons, etc. I have been taking it for about a month and I see a LOT of weight gain, despite my high motabilism or my strenuous workouts.


Subj: 4 days of terrible hives
Date: 10/21/2008
I have taken Celebrex off and on for 2 years. About 5 weeks ago I went from periodic use to 1 200 mg pill daily so that I could really concentrate on strenghtening my quads and core muscle groups after summer travel interupted my excercise routine. Pain relief was great. However I came down with 4 days of terrible hives on my scalp, face, inside my ears, neck, torso, groin palms of my hands — all the way down. Stopped the Celebrex and started Prednione which took care of the hives (but made me nuts). After reading all of these posts I realize I can’t go back to the Celebrex. (I also take Actonel and have already experienced increased gastro problems.) I’ve worked really hard to strenghten my muscles to support my arthritic joints. I focus completely on correct form to protect my joints. (I do Crossfit adapted for my limitations.) What can I take so I can continue to excercise? Because regular excercise is the only thing that makes me feel really good. Thanks.


AskDocWeb: That is something you would have to work out with your doctor unless you want to go with a non-prescription alternative. We have had good results with a supplement combination of Glucosamine HCI 750mg and Chondroitin Sulfate 600mg. However, there are a few health concerns with using glucosamine.

Subj: Drugs for rheumatoid arthritis
Date: 10/27/2008
I am a cancer patient cancer in the lympsnoid in neck for awhile I tried celabrex it gave me heart pains I have rumatoid arthrits in neck. Can any one suggest a better drug to releil pain in neck? My pain is severe.


AskDocWeb: There are a number of drugs for treating rheumatoid arthritis but they all have side effects. Here’s some of the more common pain medicines and anti-inflammatories prescribed for rheumatoid arthritis.

Nonsteroidal Anti-Inflammatory Drugs or NSAIDs for short are the cornerstone of pain management for rheumatoid arthritis. They are effective in managing pain, swelling, and stiffness. NSAIDs work by stopping the production of some of the chemicals that cause pain (prostaglandins). They are classified as “selective” or “non-selective,” based on how they work. Non-selective NSAIDs are:

  • Diclofenac (Voltaren, Cataflam)
  • Etodolac (Lodine)
  • Ibuprofen (Motrin, Advil)
  • Indomethacin (Indocin)
  • Meloxicam (Mobic)
  • Naproxen (Aleve, Naprosyn)

The main disadvantage of NSAIDs is their potential to cause ulcers or bleeding in the stomach and/or intestines. This risk can be reduced by taking a proton-pump inhibitor (a drug that reduces the production of acid in the stomach). NSAIDs often cause general stomach upset or discomfort and can also cause problems if you already have kidney failure or heart failure. If you have these conditions and are taking NSAIDs, a doctor should closely follow your progress.

Selective NSAIDs (Celebrex , Arcoxia)

These drugs are NSAIDs that have a somewhat lower risk of ulcers and stomach or intestinal bleeding yet relieve pain as well as non-selective NSAIDs.

Acetaminophen is the well-known over-the-counter drug, Tylenol. Its main advantage is its safety. When taken as directed, it has no side effects in most people. The exception is people with liver disease, who can take acetaminophen only under close supervision by a doctor.

Corticosteroids are powerful drugs for stopping inflammation. These are different from anabolic steroids like testosterone, which cause muscle growth. In rheumatoid arthritis, the benefit of corticosteroids is their suppression of the overactive immune system, which reduces symptoms and disease activity. Because corticosteroids act throughout the body and not just on the immune system, they are ideally used for short bursts to control flares of inflammation. This helps avoid their side effects.

If you have severe rheumatoid arthritis, you may need to take corticosteroids for long periods which has the potential for other problems. These include increased susceptibility to infection, increased blood sugar (diabetes), or reduced bone density (osteoporosis). Corticosteroids can sometimes be injected directly into the joints affected by rheumatoid arthritis. This is a good way to get the benefits of the drug without as many side effects.

Subj: Celebrex has been a great help
Date: 10/30/2008
I have just been diagnosed with RA. I have been taking celebrex 200mg. I found it a great source of pain relief during the first month I had taken it. Then I couldn’t afford to buy celebrex and was off it for about 2 months in which time my pain returned immensly and work became even more difficult. After being on celebrex again it has relieved alot of the pain, although not as effective as it was at first. I get so tired and to be honest some days (most actually) I just don’t want to get out of bed. And if I fall asleep during the day I could sleep for 5 hours or more. I have night sweats and sleepless, celebrex for me has been a great help with no weight gain.


Subj: Celebrex
Date: 11/7/2008
Should celebrex be taken on an empty stomach?


AskDocWeb: Celebrex may be taken on an empty stomach or with food.

Subj: Asprin with Celebrex?
Date: 11/6/2008
I have been using celebrex for several years now for osteoarthritis, now I have a very servere muscle pain in the neck the Dr have been trying to help me with trigger pt. inject. cortisone therapy my neck is not doing the job it should and I live with pain every day. Now they want to try botox, my question is, can I take asprin before bed if I take celebrex in the morning to help with my pain, or is it too much?


AskDocWeb: Aspirin may increase the speed with which your body eliminates Celebrex from your system. This may reduce the effectiveness of Celebrex or the length of time that the drug is effective. Based on information from a number of studies, this does not appear to have a significant impact on the therapeutic effect of Celebrex however, both of these drugs can cause stomach irritation and may potentially damage the lining of the stomach. The risk of experiencing these side effects may be increased when aspirin and celebrex are taken at the same time. Although this interaction is poorly documented, it is considered major in severity.

Subj: Celebrex for foot pain?
Date: 11/7/2008
I have chronic re-occurring foot pain, which comes and goes once every year or couple of years even. I’ve been to several podiatrist and they have been able to give me a diagnosis. They say it’s not “gout” although, I did have surgery on my elbow a few years ago for “gout”. I woke up the other day with a sore neck and upper back, shoulder area. I decided to take some leftover Celebrex 200mg. Just took my 2nd pill and have noticed some relief but not a lot yet. Do you think it will resolve my current pain siutation? It did work for my foot pain in the past.

AskDocWeb: If it helped in the past then it is likely to help now but to resolve the problem you need to find the cause. It’s good to rule out possible causes like gout but what did they say is causing the pain?

Subj: The best thing yet!
Date: 11/8/2008
I have been taking celebrex for about 2 months now for joint pain. I have noticed an increase in weight – generally feel bloated and puffed up and cant wear my normal clothes…I have found this page very useful and may try an alternative such as glucosamine…just started swimming again…the best thing yet!

Subj: Soma with Celebrex?
Date: 11/13/2008
Can soma 250mg be taken with celebrex or are they contraindicated?


AskDocWeb: Although we didn’t find any drug interactions listed our checker may not include every interaction that is known. Talk to your doctor, nurse or pharmacist to see if it is safe and effective for you.

Subj: Elevated blood pressure
Date: 11/18/2008
I had been taking Celebrex for the past 3 weeks as prescribed by my orthopedic surgeon while I awaited arthroscopic knee surgery for torn cartilage. Yesterday when I went to my internist for my pre-op exam to clear me for the surgery, he discovered my blood pressure was considerably elevated. My normal BP is 110 over 70, and it had gone up to 150/100. He said the Celebrex caused this and had me stop taking it immediately. Although the Celebrex really helped ease my knee pain considerably, I will not take it again.


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