About Celebrex

If you’ve used Celebrex, please help others by adding your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history. You can use the form below to add your comments, feedback or Celebrex review.

Subj: Alternatives to Celebrex?
Date: 9/23/2010
I have arthritis in my hip. The dr. prescribed Celebrex. My blood pressure was a little high a few months ago & its back to normal. My primary dr. said to take the Celebrex for awhile & monitor my BP. A dr. friend said not to take Celebrex because of the side effects. Would Aleve be better to take? Does Aleve have the same side effects? Any suggestions on other pain meds? I am on Prevacid for acid reflex. Thanks for any help.

Marcia
AskDocWeb: Celebrex is in the class of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs for short. It is a specific type of NSAID known as a COX-2 inhibitor. Celebrex is the last COX-2 inhibitor left on the market because the others were withdrawn due to safety concerns. Since there are no other COX-2 inhibitors on the market, the alternatives to Celebrex are limited to other types of medications or treatments.

Some people assume that other NSAIDs (including non-prescription NSAIDs) are safer but that has not been proven. All NSAIDs have been linked to cardiovascular events, such as heart attack or stroke, which can result in loss of life. Compared to Celebrex, other NSAIDs may have a higher risk of side effects, such as indigestion or stomach pain. However, many of the other NSAIDs are not as expensive as Celebrex. These include but are not limited to:

• Ibuprofen (Motrin®, Advil®)
• Naproxen (Naprosyn®) or naproxen sodium (Aleve®, Anaprox®, Naprelan®)
• Ketoprofen
• Diclofenac (Voltaren®, Cataflam®)
• Etodolac (Lodine®, Lodine® XL)
• Meloxicam (Mobic®)
• Indomethacin (Indocin®)
• Nabumetone (Relafen®)

If you and your doctor decides that NSAIDs are not a good choice for you, other alternatives to Celebrex may include:

• Acetaminophen (Tylenol®)
• Opiates and narcotics, such as morphine, codeine, or hydrocodone
• Corticosteroids
• Disease-modifying antirheumatic drugs (DMARDs)
• Biologic response modifiers

If you have found an alternative to Celebrex that works well for you be sure to share it with others here.

Subj: Sweating and fevers
Date: 9/27/2010
I have taken celebrex since Vioxx was discontinued for severe osteoarthritis. Over the last few years, I began sweating profusely at the least amount of exercise. I also had fevers for unknown reasons. Last fall I started having hand shaking, and loss of balance. None of my medicines were known to cause these side effects. I saw a neurologist and early Parkinson is suspected. This summer I read on line that celebrex can cause dizziness. So I stopped the celebrex just to see what happened. My dizziness and shaking are gradually disappearing. My sweating and unknown fevers are gone. Are these side effects of celebrex?

Peggy
AskDocWeb: The shaking or tremors are not listed as possible side effects of Celebrex. Dizziness, increased sweating, and fever are listed among the less common side effects of Celebrex. Fever is a rare side effect that may indicate a severe problem and medical attention should be sought right away. Other indicators of a possible severe problem are listed below. The patient information for Celebrex says to seek medical attention right away if any of the following SEVERE side effects occur when using Celebrex:

• bloody, black, or tarry stools
• change in the amount of urine produced
• chest pain
• chills
• confusion
• dark urine
• depression
• dizziness
• fainting
• fast or irregular heartbeat
• fever
• hearing loss
• hives
• itching
• mental or mood changes
• nausea
• numbness of an arm or leg
• one-sided weakness
• persistent sore throat
• rash
• red, swollen, blistered, or peeling skin
• ringing in the ears
• seizures
• severe allergic reaction
• severe headache
• severe or persistent stomach pain
• severe vomiting
• shortness of breath
• speech changes
• sudden or unexplained weight gain
• swelling of hands, legs, or feet
• swelling of the mouth, face, lips, or tongue
• tightness in the chest
• trouble breathing
• unusual bruising or bleeding
• unusual joint or muscle pain
• unusual tiredness or weakness
• vision problems
• vomit that looks like coffee grounds
• yellowing of skin or eyes

Please note that the above side effects are rare reactions to Celebrex.

Subj: Gained about 10 pounds
Date: 9/29/2010
I have been taking this drug for about 2 weeks and gained about 10 pounds or near on 5kgs, I also had bleeding in my stools for a couple of days and also had chest pain especially around my heart. So I just threw the pills out, be buggered if I’m going to gain anymore weight from all the drugs I’ve already been on over the years, and I also had lap banding which is making me more depressed as this drug has prevented the band from working properly. I just wanna say a big PHUCK YOU to the company who make this drug, and to all the government agencies out there that have allowed this horrible crap availible as a pain killer, I just wish my doc would increase my levels of oxycotin instead. DON’T USE THIS EVIL DRUG….

Bob

Subj: Miracle drug
Date: 10/1/2010
Celebrex: I take this for back pain which is due to A.S. If I ever wonder how effective this drug is at lowering pain; I only have to miss a dose and the pain grabs hold. I really think it’s a miracle drug and it keeps me totally sane. Every other drug I ever took had so many side effects, worked for me or not, I found something critical to say about it, this one works for me and I can honestly say that nothing upsets me about his one and the only side I get is the occasional acid reflux, easily controlled with yet another drug.
Mick.


Subj: Gained over 30 pounds
Date: 10/5/2010
Guess I found my answer. I have been on celebrex for a year now for inflammation for herniated L5-S1 rt annular tear at L5, DDD, and bulging disk at C5-7. I was told this had nothing to do with my weight gain. I have gained over 30 lbs even though I exercise and eat less/healthy. I was told it was another medicine yet even though I was taken off I continue to go up and down and stay sick to my stomach constantly. I am on alot of meds I’d rather not be on at any pt or time yet even though I tried stopping all meds and start one at a time I found I was unable to take my celebrex with my antidepressant bp pill, or any other pill for I was extremely sick but cont to hear the same thing from my dr..I need to cont take to help relieve inflammation and pain.

Herniated disk/tear/bulging disk

Subj: Aspirin
Date: 10/6/2010
I was given Celebrex from my Dr. for my knees. I am not suppose to take aspirin and I just had 6 uclers approx. 1 year ago. What I need to know if Celebrex contains aspirin?

Geri

AskDocWeb: Celebrex does not contain aspirin but there is an increased risk of bleeding in some types of surgery.

Subj: Increase in blood pressure
Date: 10/17/2010
I have used Celebrex for 5-6 years for severe osteoarthritis, but have been taking assorted NSAIDS for 15 years. I started having increases in Blood pressure and found that I am in Stage 3 Chronic Kidney Disesase and the Nephrologist says it is due to the NSAIDS. I tried to stop taking them cold turkey, but within 3-4 days every joint and muscle is hurting severely. If I take a Celebrex it stops. Should I be weaning off the Celebrex, or just tough it out.

K.

AskDocWeb: That is a decision best made by your doctor. Please talk to your doctor before discontinuing any prescription drug.

Subj: Heart attack?
Date: 10/18/2010
How safe is Celebrex? One of the top side effects are listed as heart attack. This is frightening.

Katherine

AskDocWeb: Although it may be news to you, it’s been six since Pfizer announced that it found an increased risk of heart attack with patients taking Celebrex. The increased risk of heart attack was reported in a long term cancer prevention study conducted by the National Cancer Institute on behalf of Pfizer. That study was halted after discovering that patients taking 400mg to 800mg of Celebrex daily had 2.5 times greater risk of experiencing major heart problems. That may sound like a lot but a review of more recent studies showed that the annual rate of heart attack for those taking Celebrex was 0.8%. The rate of heart attacks for those taking an inactive placebo was 0.52%.

Subj: Discontinued because of kidneys
Date: 10/22/2010
I am 73 and have been taking Celebrex for the last 7 years. Four days ago, I decided to discontinue it since a recent lab test indicated my kidneys were not filtering as well as 6 months previous. My doctor recommended I try taking one every other day, but I decided to terminate it altogether. I can’t believe the joint pain, muscle pain, TMJ pain, etc. that returned in full force! I didn’t realize how well this medication was masking my pain, and I will admit that I was able to do heavy, burdensome tasks like a 30-year-old, and felt terrific. Even my friends commented on my abilities, one stating that I was “going backwards” in time. They wanted to know what my secret was. As to weight gain, it didn’t seem to affect me. I do have lymph edema and wear compression stockings, but I never noticed extra swelling because of Celebrex. I truly miss the relief it afforded me, but for the record, I don’t want to compromise my liver or kidneys to the point that I must be relegated to a kidney dialysis machine!

Sharon

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