Feedback on Celebrex Side Effects and Usage from Users, page 27

About Celebrex

If you’ve used Celebrex, please help others by adding your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history. You can use the form below to add your comments, feedback or Celebrex review.

Subj: Gained weight
Date: 11/28/2010
Hi, agree it’s happened to me also- gained weight, I had shoulder pain and tennis elbow took some of my friends Celebrex that was left over. I too gained 10 pounds. I’ll take any pain or discomfort because if I don’t stop gaining weight I’ll get depressed and then be in mental pain. All in a matter of 2 weeks & I was really cutting back.


Subj: Surgery
Date: 11/30/2010
If celebrex should be stopped 2 weeks before surgery, should celebrex be given immediately after surgery to a 72 year old male.


AskDocWeb: Celebrex is sometimes given after surgery to reduce the formation of abnormal adhesions. When the inner body tissue that cut by the surgeon and starts to grow back, the tissues that binds them together are called adhesions. This is part of the normal healing process but when some surfaces fuse together that shouldn’t, it can cause serious pain and complications. Taking Celebrex after surgery can reduce the possibility of those painful adhesions.

Subj: Celebrex compared to tramadol?
Date: 12/10/2010
I have been diagnosed with a herninated disc and spinal stenosis. I am in a lot of pain and currently taking tramadol. My doctor started me on celebrex. Does celebrex relieve pain like tramadol?


AskDocWeb: Both medicines help control pain but they work very differently. In a 2006, Pfizer conducted a clinical trial comparison of the two drugs. The study concluded that Celebrex was more effective than tramadol and also better tolerated.

Subj: TMJ and Celebrex
Date: 12/12/2010
I was diagnosed with TMJ that was giving me ear pain. Dr prescribed 200mg Celebrex for 14 day and then to use as needed. Towards the end of the 2 weeks, I was getting nauseaus from the Celebrex. I stopped taking got very bad pain that went up and down my entire back, including my neck. Am dealing with some constipation related to the Celebrex. The pain in my back is bad, I am not taking any painkiller. Also, prior to being prescribed Celebrex, I told my dr I am allergic to Sulfur. I have had bad reactions to Augmentin that resulted in extremely high liver enzymes. I currently have been off Celebrex for 3 days and very tired and fatigued. My back is very achy and I have no appetite and have some stomache pain. Nausea is gone. Can this be related to Celebrex and how long before it is gone from my system?


AskDocWeb: Nausea is a common side effect of Celebrex, which occurs in 4% to 9% of patients using this drug. It may take up to two days for your body to completely clear the Celebrex from your system. However, constipation is listed as one of the potential side effects of Celebrex that should be reported to your doctor.

Subj: Twitching eye, blurred vision, blood restriction to hands
Date: 12/29/2010
Celebrex brings some relief to my Morton’s Neuroma and some arthritic issues. Side effects have included a twitching eye, a little blurred vision, slight blood restriction to my hands. It does, however, mask the immense pain in my foot and hands. I don’t trust it for long term… My side effects are increasing on an inappropriate rate. At times, I feel like I am anticipating a heart attack. Fortunately, I am having surgery in a few days and hopefully will not have to rely on the drug to get me through a work day.


Subj: Clotting issues
Date: 12/29/2010
My question is this. I have Factor Five Liden defeciency. I had a DVT diagnosed six years ago and was put on therapeutic coumadin. I have taken ibuprofen since I was 10 (roughly 15 years now). I continued taking ibuprofen with the coumadin for the first two years after the diagnosis because no one said anything. But then a new doctor saw them together, freaked and insisted I stop taking the ibuprofen. So I did, but after a year I started taking the ibuprofen again cause nothing was working for my aches and pains. So, I went back to what I knew worked. It’s been three years and I’ve been taking the two together without any problems. Just recently I encountered yet another doctor that was made nervous by the combo. So he switched out my ibuprofen for Celebrex. But as far as I can tell Celebrex warnings are just as bad if not worse then ibuprofen when it comes to clotting issues. So, my question is this…..Which is worse when it comes to clotting issues, Celebrex, or Ibuprofen?


AskDocWeb: The answer to that varies from one person to the next because these drugs do not effect everyone in exactly the same way. While Celebrex may not cause any bleeding problems for most people, somewhere between 3.9% and 13.4% of patients experience clotting issues. So which group are you in?

Subj: Diarrhea
Date: 12/29/2010
I have been on 200 mg of celebrex for about 3 yrs. 6 mos. ago i started getting loose stools which finally developed into diarhea for one month before I had a stool culture done. it was nothing bacterial. i stopped the celebrex for a month and the problem went away. However, the pain is bad. i am 71 yrs old and with celebrex could walk 7 or 8 miles without a problem. Now I can only go 3 miles and have to call for a ride back home from my kids or grandkids. So now i looked on this site and decided to start celebrex again and try 200 mg every other day to see if it will work without the diarhea. Thank you for this site. It made me feel more confident about what i am doing.


AskDocWeb: Please remember that any change in dosage should be discussed with your doctor.

Subj: Anti-inflammatories and bone grafts
Date: 12/30/2010
I had a total knee replacement which included a bone graft. I was put on celebrex after the graft was completely healed as I needed to have my other knee replaced. After two months on celebrex my surgical knee starated popping and hurting. X-rays showed that the graft had become necrotic and the tibial plate was on a 30 degree angle. Had to have the knee replaced again. Does anti inflammatories cause harm to bone grafts?


AskDocWeb: Some research has shown that using anti-inflammatories can interfere with bone mineralization and prolong recovery. According to a presentation by Amol Saxena, DPM, at the Palo Alto Medical Foundation, “Anti-inflammatories actually decrease bone mineralization, so patients prone to stress fracture or who may have one, should actually avoid anti-inflammatories. They should however take the minerals, calcium, and zinc, which seem to help with bone metabolism.” Mineralization is the process where an organic substance is converted to an inorganic substance, in this case the formation of bone.

Subj: Anemic
Date: 1/4/2011
I have been taking Celebrex for approx 6 months, I had blood work and a month ago I found out I am now anemic. Actually, quite a bit down from 15 to 9..I have just read Celebrex can cause Anemina. The last time I was anemic was 34 years ago during my last pregnancy. I am going to see my GP but I expect he will just poo poo but its strange after 5 months I became anemic should I stop?


AskDocWeb: Although rare, anemia was noted in the clinical trials of Celebrex with an incidence rate of 0.6% compared to 0.4% of those taking a placebo. The question of stopping or not should be decided by you after you discuss this concern with your doctor.

Subj: Severe thigh pain and fingernails are peeling
Date: 1/5/2011
I have been on 200 mg Celebrex 1x day (morning with breakfast) for about a month and a half. I have been having severe thigh pain (primarily right side..) for probably 2 weeks. ALSO for some crazy reason my fingernails are peeling terrible and this has never EVER been a problem for me. Do you think this is the medicine? Since the pain is just the right leg, that seems odd to me that it would just be the one place. Please let me know your thoughts.. thank you..


AskDocWeb: Any pain that is severe should be reported to your doctor. If you have never experienced peeling fingernails before it can be a little disconcerting. Fingernails grow in layers and under certain conditions the layers can separate and split off. There are several reasons for this and in general they are categorized as medical causes or non-medical causes. The medical causes are usually fungal infections or bacterial infections like psoriasis. The non-medical causes include exposure to harsh chemicals, harsh environment and aging. If your condition has a medical cause you may want to check with your doctor or a dermatologist. Otherwise you might try applying vitamin E or jojoba oil to the nail in order to replenish the natural oil and moisture content of the nails.

Subj: Alopecia spots
Date: 1/6/2011
I have been using celebrex for approximately 6 weeks. At my hairdresser today he showed me 2 different alopecia spots. I have never had this before. Can this be caused by Celebrex?


AskDocWeb: That is a possibility, alopecia has been reported in less than 2% of patients taking Celebrex.

Subj: Really bad headaches
Date: 1/26/2011
I started taking Celebrex, 200 mg, last month. Within a week or so I started having really bad headaches. At first I didn’t think to much about it because I occasionally would have a 3 day migraine but I was having a 3 day headache, then one day with no headache, then a two day headache and then almost every day I would still have a minimum of a dull headache when my head wasn’t killing me. Then I went to the dentist and they took my blood pressure and it was 148/90 which was extremely out of the ordinary as my blood pressure is normally on the low side, around 110/70. So I started monitoring my blood pressure and it was consistently higher and the headaches were persistent. I decided to stop the Celebrex and the headaches stopped within 24 hours and my blood pressure was back to normal in a few day. The bad part of all this is I have a herniated disc in my lower back and arthritis in my back and neck and the celebrex worked wonders. Now what would have similar results without the side effects???


AskDocWeb: Celebrex is the last Cox-2 inhibitor left on the market. Since there are no other COX-2 inhibitors on the market, the alternatives to Celebrex are limited to other types of medications or treatments.

Some people assume that other NSAIDs (including non-prescription NSAIDs) are safer but that has not been proven. All NSAIDs have been linked to cardiovascular events, such as heart attack or stroke, which can result in loss of life. Compared to Celebrex, other NSAIDs may have a higher risk of side effects, such as indigestion or stomach pain. However, many of the other NSAIDs are not as expensive as Celebrex. These include but are not limited to:

  • Ibuprofen (Motrin®, Advil®)
  • Naproxen (Naprosyn®) or naproxen sodium (Aleve®, Anaprox®, Naprelan®)
  • Ketoprofen
  • Diclofenac (Voltaren®, Cataflam®)
  • Etodolac (Lodine®, Lodine® XL)
  • Meloxicam (Mobic®)
  • Indomethacin (Indocin®)
  • Nabumetone (Relafen®)

If you and your doctor decides that NSAIDs are not a good choice for you, other alternatives to Celebrex may include:

  • Acetaminophen (Tylenol®)
  • Opiates and narcotics, such as morphine, codeine, or hydrocodone
  • Corticosteroids
  • Disease-modifying antirheumatic drugs (DMARDs)
  • Biologic response modifiers

Because of the variety of health concerns that have to be taken into account, check with your doctor for the best choice for an alternative to Celebrex.

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