Ibuprofen Users Comment on Side Effects and Usage, page 3

Ibuprofen Feedback

If you use Ibuprofen, please help others by adding your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.

Subj: Notably more confused
Date: 7/7/2009
My great-grandmother suffered a stroke and she is bedridden. After we began giving her Motrin to help with the pain in her arm she became notably more “confused” and quite angrily at times. She doesn’t seem to have a fever either so I’m not sure if the ibuprofen added to her already unstable mind she has aquired from the stroke.


Subj: Bloody discharge
Date: 7/20/2009
I take ibuprofen occasionally, sometimes 2 – 3 times a day if needed. I have noticed a bloody discharge occasionally, either from the vagina or bladder. Could this be as a result of taking the ibuprofen?


AskDocWeb: That is a possibility but it is also possible that it may be something that needs medical treatment so check with your doctor. Nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen have been shown to increase bleeding during surgeries, which may prompt practitioners to discontinue their use before surgical procedures. Studies show that those who take high doses of Ibuprofen have increased bleeding as soon as three days after beginning treatment.

Subj: Flu like symptoms
Date: 8/12/2009
I recently started taking Ibuprofen for a persistent pulled muscle and wasn’t paying attention to what I was doing. I was dosing myself at 2-3 grams per day (10-15 pills)for 5-6 weeks. About a week ago I came down with what I thought was the swine flu or regular flu. I had a bad fever (nearly 103 at one point) and intermittent chills and sweats as well as a non-stop headaches and all over body pain. My doctor was not sure about the flu (tests were negative). Finally on Monday it dawned on me that I was over medicated so I researched side effect of ibuprofen overdose and low and behold and I had many of those symptoms. What had gotten me questionning the flu diagnosis was that there was no involvement of the nasal, gastro or respitory systems. When I stopped taking the ibuprofen on Monday I’ve improved remarkably. The fevers and body aches are subsiding and I’m fairly convinced that the ibuprofen was the problem.


Subj: Problem with coating on ibuprofen
Date: 8/20/2009
My son has taken Ibuprofen since he was little in the liquid form or children tablets. Tonight I gave him 200mg ibuprofen with the coating he had a serve reaction to it and was taking to the hospital. He is 7 and 61 pounds. The Doctors thinks it is the coating on the ibuprofen. Has anyone else had this problem?


AskDocWeb: Yes, there are a few reports of problems like this. At this point we aren’t sure if this is a rare reaction to the coating on the tablet, an allergic response to the ibuprofen, or (least likely) both. More research is needed into the coatings used for pills. While it is rare, it is possible to develop an allergy to a drug after many exposures, even after years of use. The symptoms of a severe allergic reaction to Ibuprofen may include:

  • asthma (wheezing)
  • facial swelling
  • hives
  • shock

If you suspect an allergic reaction after taking Ibuprofen, you should call 911 so that help can arrive as quickly as possible and then take Benadryl. The facial swelling can spread to your throat, making it impossible to breathe.

Subj: Diarrhea, indigestion, and blood in stool
Date: 8/26/2009
I have used ibuprofen, 3 times a day for 3 years. I have server headaches. I am having stomach issues, constipation and then diariah, indegestion like pains and today I had a timy bit of blood in my stool. Can the ibuprofen be causeing this?


AskDocWeb: Diarrhea and indigestion are listed as possible side effects that may go away with continued use. The blood in your stool should be reported to your doctor.

Subj: Ringing in ears
Date: 8/28/2009
I have had ringing in my ears for the last month since I have been taking Ibuprofen and also some dizziness. I stopped taking it 2 days ago but still have the ringing, how long are side effects likely to last?


AskDocWeb: If the ringing in your ears was caused by the Ibuprofen then discontinuing should bring relief within a few days. There is also a possibility that the ringing is unrelated to the drug. Every year about 12 million people seek medical help for tinnitus. So far, the cause of tinnitus is unknown.

Subj: Hot flashes
Date: 8/29/2009
It is such a relief to read the feedback on hot flashes as a side-effect of Ibuprofen use. I avoid any form of medication, but the dental pain after two root canal treatments was so severe that I decided to take Ibuprofen for the pain. After two weeks of use I started to experience hot flashes that were both intense and persistent. In the first week, the flashes occurred intensely and almost continuously throughout the day – quite a frightening experience. I have not consulted my doctor because I could not face the prospect of being told that I was experiencing the menopause. The symptoms coincided with the use of Ibuprofen (I take no other medication), and have slowly improved after stopping.


Subj: Hot flashes
Date: 9/22/2009
I am 64 years old and experience hot flashes for 24 hrs plus after taking one 800mg Ibuprofen.


Subj: RE: Hot flashes on ibuprofen
Date: 10/8/2009
I came across this site because I was looking up what causes getting really warm after taking ibuprofen. I am a 25 year old female and it’s been happening to me since I was 10 years old! Or that’s the earliest I can remember. It happens with tylenol as well. It’s miserable. I become really hot and I sweat like crazy. When I’m sick, there is no point in taking it to break a fever. It makes me more miserable. I have no idea what’s causing it.


Subj: Gout and diabetes?
Date: 10/8/2009
Hi, I’m a twenty nine years old male from Yap State, Federated States of Micronesia and I have been taking ibuprofen since I was twenty 23 years old…I know to young to be getting gout attacks. Well my uncle has the same problem, Gout, and worse …diabetes. Right now his in the hospital, they say both his kidneys has failed. I assume that he was prescribed the same meds cause our hospital here is small don’t have a lot of options. So I guess my question is could it be that his condition was caused from taking Ibuprofen? Oh! I forgot to mention that he was refered to Manila Philippines for a heart surgery before his kidneys failed to function. He’s refusing a kidney transplant. He’s wish is to leave it up to god to decide if lives or not.


AskDocWeb: We have seen nothing to suggest that Ibuprofen might cause Gout or diabetes.

Subj: Effect on immune system?
Date: 10/28/2009
I was wondering if there is any data regarding the effect ibuprofen has upon the immune system. Specifically, I wonder if taking it to reduce the discomforts of a cold or the flu reduces your body’s immune system’s ability to fight off these fairly common conditions? In other words, will taking ibuprofen make you more comfortable with the trade off of being ill longer?


AskDocWeb: That seems to be a real possibility and the effect may be stronger than you suspect. It is currently being studied. A study by researchers in the Czech Republic reported that giving acetaminophen, the active ingredient in Tylenol, to infants weakens the immune response to vaccines. (October 17, 2009, edition of The Lancet)

Richard P. Phipps, Ph.D., (University of Rochester Medical Center) cautions that during flu vaccination season taking common pain killers at the time of injection may blunt the effect of the shot and have a negative effect on the immune system. The list includes Advil, Tylenol, Aspirin, and Ibuprofen.

Phipps says his research tested whether production of antibodies is reduced by over-the-counter pain relievers. He found that a variety of pain relievers seemed to dilute the production of necessary antibodies to protect against illness.

“What we’ve been saying all along, and continue to stress, is that it’s probably not a good idea to take common, over-the-counter pain relievers for minor discomfort associated with vaccination,” Phipps said. “We have studied this question using virus particles, live virus, and different kinds of pain relievers, in human blood samples and in mice — and all of our research shows that pain relievers interfere with the effect of the vaccine.”

The study noted that treatment during the earliest stages of inflammation – or when the first signs of pain, swelling, redness or fever would occur – had the most detrimental effects on the immune system. The connection between NSAIDs and antibody production is still being pursued. Phipps said researchers believe ibuprofen, in particular, affects lymphocytes’ ability to produce antibodies.

Subj: Tested positive for THC
Date: 10/31/2009
I was taking alot of ibuprofen and tested positive for THC and was fired from my job. I went straight to my family doctor so he could perform a drug test. Is blood more accurate than urine and how long does it takes ibuprofen to exit your system compared to real THC?


AskDocWeb: Yes, a blood test is much more accurate than a urine test. Ibuprofen has a half-life of about 2 hours. The duration of action is between 4 and 8 hours and should be completely out of your system within 24 hours.

Subj: Acute nausea?
Date: 11/12/2009
Having taken Ibuprofen regularly for an extended period of time, is it at all possible for acute nausea to occur after several months or even a year?


AskDocWeb: Yes, side effects can appear after many months of treatment. Severe or persistent nausea should be reported to your doctor.

Subj: How many tablets
Date: 11/30/2009
How many tablets of ibuprofen would you have to take to become ill and have to go to hospital without having ANY long term damage? I’m 16 and need this for a school project I will not be attempting it. Thanks,


AskDocWeb: Sorry Caroline, our focus here is on side effects, not drug abuse.

Subj: Vaginal spotting
Date: 12/6/2009
Have had a serious back injury & also recently fell & broke my wrist in 2 places. Lots of pain, so took 600 mg of ibuprofen 4x daily for about 2 weeks as recommended by the orthopedist, when I showed vaginal spotting. Could this be related to the ibuprofen?


AskDocWeb: Ibuprofen actually has the opposite effect. Women that use IUD’s are often advised to use Ibuprofen to help decrease spotting and irregular bleeding.

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