Feedback on Nexium Side Effects and Usage, page 3

Nexium Side Effects

If you’ve used Nexium, please help others by sharing your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.
Subj: Bowel movement colors
Date: 8/4/2005
Can Nexium be causing irregular color in bowel movements? Such as pale, tan, and a sort of bi-plaid mix effect of both pale and rust color stools?


AskDocWeb: Nothing is listed for a change in the color of stool. Have you changed anything in your diet? If you take supplements, some of them may pass through your system undigested and appear as colored spots in your stool.

Subj: Nexium and numbness
Date: 9/26/2005
I have been on nexium for several years and it works good. About 11 months ago I woke up and was numb in my left side down to my – actually the entire numbness took about 3 days to occur – originally I thought my foot was asleep. In reading side effects of my medicines, nexium says it can cause numbness/tingling of feet. Mine is actually the left side from waist down. They have done several MRIs but in reading this I was wondering if this has ever happened with nexium before. Should I go off it? I tried before but had acid reflux again when I went off.


AskDocWeb: Sounds like you need to have a scope done to see exactly what the problem is and how to resolve it without Nexium.

Subj: Chest pain
Date: 10/21/2004
I just started on nexium only today my pain in my chest is so bad that I’m unable to eat or drink makes for a miserable time. I was wondering if anyone had that bad of pain like me and how long it takes “nexium” to make it go away.


AskDocWeb: Chest pain is not listed as being a side effect of Nexium. Make an appointment immediately with your physician or go to the walk-in to be seen today if your physician is unable to see you right away.

Subj: Abdominal pain
Date: 11/10/2005
I have upper abdominal pain and discomfort sometimes going through to the back. Started after thyroidectomy. Am taking Nexium 20mg in the evening before sleep but next morning I am nauseous. Should I have an endoscopy or hp breath test?


AskDocWeb: You should be checked out by your physician on this. It could be several things, a simple ulcer for instance. You may need a scope test done to see of there is anything wrong, but do not ignore this pain. Your body is telling you something. And Nexium is not likely to cause the morning nausea.

Subj: Frequent sore throat
Date: 11/17/2005
I have been taking 40mg of Nexium for over a year now and have gained 12 lbs. and don’t eat any more than usual. Before taking Nexium, I experienced chest pain and shortness of breath daily. Now I am having sore throat frequently. I read that acid reflux could be the cause but I have an acute case of sinuses also with a constant drainage that could also cause sore throat. Do others complain about having this problem with acid reflux?


AskDocWeb: No, a sore throat is not caused by Nexium. Sounds like your sinus infection is draining down the back of your throat. That will cause throat irritation.

Subj: Nexium headaches
Date: 1/4/2006
How long after stopping nexium does it take for headaches to stop?


AskDocWeb: 3.8% of people using Nexium reported headaches. They should not last more than a couple of days. If it lasts more than 3 days, see your doctor. In the mean time try using a heating pad on your neck and shoulders for 15 to 20 minutes to get some relief.

Subj: Nexium Question?
Date: 1/8/2006
I have been taking Nexium for approx. 2 months now…after several GI tests, etc…I take 40 mg. a day and it seems to have helped quite a bit. In the last week, I seem to have developed what feels to be muscular aches and pains mostly in my arms and hands…and it comes on at night…sometime after dinner. I am just “dragging” my body in the evening. Has anyone else had this happen…and could it be the Nexium? Thank you.


AskDocWeb: Yes, some Nexium users experience fatigue (less than one percent).

Subj: Long term use of Nexium
Date: 1/9/2006
I have been taking Nexium for several years and it has helped my heartburn problem about 70% however, over the last three years I have had severe bowel problems, back and forth with diarrhea and constipation, losing a lot of weight very quickly, B12 deficiency, and anemia. I have had every non pleasant test there is with no diagnosis yet. I have read several articles lately suggesting that long-term use of Nexium can cause colitis and several of the symptoms noted above. What is your thought on this? My doctors have not even entertained the fact that my problems could be related to Nexium?


AskDocWeb: In a small number of cases long-term use of Nexium has caused diarrhea, abdominal pain, bowel irregularity, constipation, anemia, vitamin B12 deficiency, and changes in weight (a decrease for some and an increase for others). It seems you are one of the few who do not tolerate this med well.

Subj: Birth defects
Date: 1/17/2006
You mentioned that there have been several reports of babies born with defects to women who had taken Nexium. Could you please tell me where you obtained that information? Thank you,


AskDocWeb: Yes, there have been sporadic reports of congenital abnormalities occurring in infants born to women who have received nexium during pregnancy. That information came from the Physicians Desk Reference. It says that women should not use Nexium unless there are no other alternatives if they plan on getting pregnant.

Subj: GERD, fatigue and pain
Date: 1/17/2006
I have been on nexium 40mg twice daily for about 5 months for GERD. For the past month I have had shoulder fatigue and joint pain. For the entire 5 months I have been having pain in my testicles. I read a post dated 7/7/05 that has similar symptoms. Are these symptoms caused by the nexium. I will try going off of the nexium for a few days to see if the symptoms go away.


AskDocWeb: It is possible, fatigue is a listed side effect of Nexium. Pain has been attributed to Nexium in the back, chest and abdominal areas.

Subj: Nexium and abdominal pain
Date: 1/21/2006
Hi, this is my third day on nexium 40mg. I am having upper abdominal pain. The pain feels is kinda like contractions at the top of my stomach. What should I do? Does this medicine effect the liver? I had an adverse reaction to Keytek and now I find out that this medicine has killed one person, ect.

AskDocWeb: Abdominal pain is one the most common side effects of Nexium (along with headache, diarrhea, nausea, flatulence, constipation and dry mouth). Nexium is metabolized in the liver and acute liver failure is listed as a rare side effect.

Subj: Long-term use of Nexium
Date: 1/21/2006
Doctor has me on nexium long-term for GERD and Barrets. He informed me that I would need to be on it for life. Is it ok to take this medicine for that long, seems like several responses on this discussion thread elude to the fact that it should not be taken past 6 months?

AskDocWeb: The reason you see that six month time frame mentioned so often is that the long-term studies lasted 6 to 12 months. It seems that anything over 6 months is considered long-term. We suggest you let a medical professional (your doctor) decide how long you can take Nexium.

Subj: Fever, burping and nausea
Date: 1/31/2006
I started taking Nexium a about five days ago, and about 1 day into it, I started getting a mild fever feeling in my head (my face gets flushed). Now violent burping has accompanied it, and some nausea. I know the nausea is normal, but what about the rest of it? I took Nexium once before and never had problems. But this time, I am taking Colace and FiberCon with the Nexium. Would that make a difference?


AskDocWeb: It sounds like Nexium isn’t working for you the way it used to, make an appointment with your physician.

Subj: Nexium side effects
Date: 2/19/2006
I started taking nexium 40mg 18 months ago after getting a endoscopy I have a hiatus hernia and L.A. grade C esophagitis. I had chest pain before nexium and upper abdominal pain in the region of the L.E.S. I was 190 lbs when I first started taking nexium I am now 242 lbs. I still have GERD and chest pain. I have seen every doctor about the chest pain I can and they can find no reason for it short of GERD also I have seen a psyc. and have been cleared.

I am currently on 80mg of nexium for the last 3 months and my stomach pain is still with me. I have had ultrasound’s x-ray’s nothing has been found. I have taken protonix, prevacid, and prilosec with no results. My questions are why would I still have pain in the stomach could it be a paradox reaction due to no acid? What are the rebound reactions with stopping nexium and should I really be feeling so crappy after this long. I am negative for an infection of my stomach lining and I am 6’1″, 27 years old to give a background. My family has a history of esophagitis, Barret’s, GERD and cancer.
I do understand I present with a complex array of problems. I hope maybe some people may find hope they are not alone with the complexity’s that can present with reflux. I am currently taking 1-2mg klonopin and 80mg nexium . Thanks for your time,


AskDocWeb: Klonopin is known to cause abdominal pain in less than 2% of users.

Prevacid is known to cause abdominal pain in 5% of users.

Prilosec is known to cause abdominal pain in 2% of users.

Protonix is known to cause abdominal pain in 3% of users.

Subj: A choice between heartburn and gastritis?
Date: 2/25/2006
I have been taking Nexium for as long as it’s been available (and before Nexium I was on Prilosec). For years I have been complaining to my doctors about severe abdominal pain. I have an excessive amount of trapped gas and symptoms of gastritis. The symptoms are debilitating. I recently thought about the possibility that Nexium was causing my pain so I stopped taking it. Within a couple days the intense pain I’d been experiencing seemed to calm down. Then came the heartburn. It was so bad it radiated up my collarbone up into my neck. My doctor prescribed Zantac 75mg but the heartburn keeps coming back . . . and it’s bad! Is there any other medication I can take like Nexium without the side effects? I would think Prilosec would have similar side effects? I tried Pepsid AC and it didn’t work. Do I have to choose between heartburn or gastritis?


AskDocWeb: You could have a hiatus hernia. Discuss this possibility with a gastroenterologist instead of your physician. Try drinking milk, and avoid laying down after eating. You could also try loosening your belt a notch. It’s surprising how much acid can be pushed upwards if your belt is too tight.

Subj: Nexium and vomiting
Date: 2/28/2006
Does nexium interfere with normal vomiting if there is an upset stomach? I had seriously strong stomach cramps, such that I would compare them to the strength of uterine contractions during labor. I was unable to vomit for several hours. I finally was able to throw up and then the cramps were gone and I was able to go to sleep.


AskDocWeb: Yes, it can interfere with vomiting.

Subj: Nexium for GERD
Date: 3/5/2006
I’ve been on Nexium (40 mg. daily) for almost four years due to GERD. It has been great and really helps ease heartburn; however, I’m worried about the consequences of being on this medication for so long. I really do not want to quit taking Nexium – should I be concerned?


AskDocWeb: The only long-term concern listed is Atrophic gastritis and that has been noted only occasionally. Atrophic gastritis is a long-term inflammation of the stomach, the main symptom of which is a pain just below the breastbone. Read more feedback about Nexium.
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