Feedback on Nexium Side Effects and Usage, page 45

Nexium Side Effects

If you’ve used Nexium, please help others by sharing your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.
Subj: Wind and burping?
Date: 8/29/2010
My daughter started on Nexium for reflux at 5.5 months and it has definitely reduced her pain levels and gulping/swallowing. She is sleeping better. My question is, can it cause wind/burping as the burps seem to have got worse since she started on it, and are still causing her significant discomfort.

AskDocWeb: Flatulence or gas is one of the possible side effects of Nexium. Burping is another matter. Reducing the normal production of stomach acid results in the production of gas. Many physicians consider burping a natural body function and see no reason to suppress it. However, there are a few things that can be done to reduce burping and belching.

  • Get checked for lactose intolerance
  • Drink water, juices and tea instead of soda or beer.
  • Avoid chewing gum
  • Avoid sucking on hard candies or lollipops
  • Avoid prolonged breathing through the mouth
  • Avod drinking too much liquid with meals
  • Avoid swallowing air

It is possible to swallow up to 5 ounces of air every time you swallow. Air that is swallowed does not usually reach the stomach and is expelled from the esophagus through a burp. Remember that burping really is a normal body function.

Subj: Bruise easily
Date: 9/2/2010
I have been taking Nexium for several years and recently stopped it. My acid reflux came back and the Nexium is not giving me relief this time around? Additionally, I bruise VERY easily and it has been suggested that this is a side effect of taking Nexium. Is that true?

AskDocWeb: If you bruise easily it may be a sign of vitamin deficiency (C or K), or a blood disorder but it is not one of the side effects listed for Nexium. Aspirin, warfarin or anti-inflammatory medications, as well as ginkgo biloba may also cause the skin to bruise easily. Please discuss this with your doctor.

Subj: Gallbladder problems, gallstones?
Date: 9/6/2010
I have been on nexium for about 4 years. I now have a 12mm gallstone. I am wondering if Nexium has been linked to gallbladder problems. Thanks,

AskDocWeb: Nexium has been linked to a higher rate of hip fractures in the elderly and a higher rate of gastrointestinal infection but not gallbladder problems.
While researching your question we came across another warning that you may not have heard about. The FDA is warning consumers not to mix certain heartburn drugs like Prilosec with Plavix. Tests have shown that Prilosec (over the counter) and Nexium (prescription) interfere with the ability of Plavix to block platelet aggregation (it’s anti-clotting effect). Studies have shown that the drug interaction may cause the effectiveness of Plavix to be reduced by 50%. Plavix is used to prevent the blood clots that typically lead to heart attacks and strokes.

Subj: Really tired
Date: 9/6/2010
I have been on Nexium for about a month now and I have been feeling so tired that I have a really hard time getting through the day. I have checked the side effects online to see if tiredness is one of those but I can’t seem to get an answer. Can Nexium make me tired or could it be something else?

AskDocWeb: It could be either one. Under adverse reactions for Nexium, fatigue is listed as being reported by less than one percent of patients taking Nexium. Of course it could also be caused by something else.

Subj: Stopped using it suddenly
Date: 9/6/2010
I have been taking Nexium for years. When I read the FDA findings about bone and joint fractures caused by long-term usage of nexium (PPT) I stopped using it suddenly. I realized after that I should have stopped slowly. I have been uncomfortable for weeks with heartburn and other symptoms since I stopped taking Nexium a few weeks ago. It feels as though my body is going through withdrawals. I would like to stay off of Nexium for a while but should I start again and then reduce the dosage or will these symptoms eventually go away.

AskDocWeb: It doesn’t happen to everyone but some people experience rebound hyperacidity when discontinuing Nexium where the stomach over-produces acid for a while. According to an article in the journal Gastroenterology (July 2009), 40% of patients who stopped taking Nexium suddenly after a few months of use experience this rebound affect. Please discuss this with your doctor because the condition for which you were taking Nexium may still need treatment.

Subj: No side effects
Date: 9/9/2010
I’ve been taking Nexium once a day (40 mg) for about 6 months, and I haven’t experienced any side effects. I have heard that it shouldn’t be taken over a long period of time.


Subj: Drink alcohol?
Date: 9/10/2010
whilst on Nexiumhp7 is it alright to drink alcohol?

AskDocWeb: Alcohol is not mentioned in the patient information for Nexium Hp7 (Esomeprazole, amoxycillin trihydrate and clarithromycin).

Reply to Joan
Date: 9/13/2010
Joan, My husband also is going thru the trial with low platelets and red/white blood cells since taking Nexium for years. The doctor told him (after the annual physical) to stop taking Nexium. But I wonder if they are a little late as his platelets have continued to fall. I don’t know the answer either. How long does the drug REALLY take to get out of their systems?

AskDocWeb: The half-life of Nexium ranges from one to one and a half hours, it varies by individual. That’s the amount of time for half of the drug to leave the body. As a general rule, once a drug is discontinued it has no pharmacologic effect after a period of time equal to 5 times its half-life.

Subj: Numbness, joint pain, headache, shortness of breath, and fatigue
Date: 9/17/2010
I have gastro problem which was originally diagnosed as gallbladder problem. I am taking 7 days Nexium Hp7, after the first pill, I feel the previous pain gone however I have several side effects like: numbness at the lower part of stomach, joint ache everywhere in my body, headache, shortness of breath and feeling very weak after just taking the second n thurd pills. I am going back to see my Dr on Monday to tell about all of these symptons. I now I have to take bed rest due to no energy and aching all over my body.


Subj: Headache
Date: 9/19/2010
I’ve been taking nexium for about 2 1/2 months. I’ve had a headache for weeks or months. Nothing gets rid of it. It’s just a dull ache in the forehead area. It comes and goes, but it’s more here than not. I thought it was because I had strep, but once the strep was gone the headaches continued. Could these dull headaches be the Nexium? I’ve taken others over the years without this problem. Thanks in Advance!

AskDocWeb: It could be, headache is listed as the number one side effect for Nexium.

Subj: Something stuck in my throat
Date: 9/20/2010
I have been taking nexium for 5 years now and all along it has worked great for my reflux. Within the past few weeks of taking it I have noticed tingling on my tongue and been feeling like a lump or something stuck in my throat when I swallow. Also chest feels tight and have to take deep breaths. Can I just suddenly become allergic to nexium after 5 years?

AskDocWeb: Yes, people have been known to develop an allergy or allergic reaction to something even after many years of exposure. Although allergies and allergic reactions have been around for 160 million years, allergists still don’t know exactly why or how allergies develop. It has something to do with a specific antibody (immunoglobulin E or IgE) but a lot of research is yet to be done. Most allergic reactions are minor and not life threatening but an allergic reaction to drugs can kill so check with your doctor.

Subj: Retaining fluid
Date: 9/21/2010
Started Nexium 45 days ago. Best thing ive ever done for my ulcers. I have not had any side effects until the other day a friend pointed out that my feet & ankles looked swollen. They do not hurt and are not huge by any means but it does look like im retaining fluid. Any suggestions. Nexium is the only thing that has helped me since highschool 7 im 44 yrs. old. Thanks so much.

AskDocWeb: Swelling of the ankles or feet has not been associated with Nexium but it can be an indication of circulatory problems so find out what your doctor thinks.

Subj: Leukopenia, headaches and sluggishness
Date: 9/21/2010
I’ve been taking Nexium 40mg daily since the fall of 2007 (just shy of 3 years). It has been very effective at controlling my reflux. Over the past year or so I’ve become much more conscious of recurring headaches and overall sluggishness. At my last doctor’s appt in July 2010, I was diagnosed with Leukopenia (low white blood cell count, just below the bottom range). My blood work besides this was picture perfect – kidney & liver function fine, cholesterol excellent, blood pressure great, all vitamin and glucose levels were normal. My doctor advised that I see a hematologist to follow up. But it was not until now that I began to investigate the relation of my symptoms to long term Nexium use. I immediately stopped the medication just over a week ago, and still having headaches and fatigue. I’m wondering if it is all related. Any thoughts?

AskDocWeb: It may be, Leukopenia is listed as one of the adverse events that were reported as possibly or probably related to Nexium with an incidence rate of less than one percent. Discontinuing Nexium suddenly may result in rebound hyperacidity.

Subj: Pain in breast
Date: 9/23/2010
I have been on nexium for 6 months and now have been having pain in the upper part and going down the left side of my breast, had a mammogram and it was good. Could this be a side effect of this medication?

AskDocWeb: Chest pain is listed as one of the possible severe side effects of Nexium that should be reported to your doctor immediately.

Subj: Difference between acid reflux and hiatal hernia
Date: 9/26/2010
I’ve been taking nexium since back in the 1980s. I was told I had a heiatle hernia, I have not really seen any noticable change, I’ve question; wheather I should continue takeing this pill and what is the differance between acid reflux, and a hiatle hernia?

AskDocWeb: A hiatal hernia is the physical protrusion of the upper part of the stomach into the thorax through a tear or weakness in the diaphragm. Acid reflux is defined as a set of chronic symptoms or mucosal damage produced by the abnormal reflux of stomach acid back up into the esophagus. Read more feedback about Nexium.
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