Feedback on Retin-A Side Effects and Usage, page 61

About Retin-a

If you’ve used Retin-A, please help others by adding your feedback. What would you tell your best friend about this product? Please remember that we do not give medical advice. That is for your local health care provider, who is familiar with your medical history.

Subj: Skin has a hazy gray color
Date: 12/30/2009
I have noticed my skin having a hazy gray color to it around my lips, chin, and eye area after using the Retina Micro product. What could be causing this?


AskDocWeb: Most likely it is caused by sun exposure over time or your hormones. Typically skin becomes discolored because the body produces either too much or too little melanin. Aside from exposure to sunlight and hormones, your skin can become discolored because of skin damage, such as remnants of blemishes, wounds or rashes (See Cutis, August 2005, pages 19-23). This is especially true for those with darker skin tones.

Subj: Irritation and redness
Date: 12/31/2009
Hi, actually I dint have much acne at all, I am using retin A 0.025% for a week and a half and I first got lot of acne and inflamation…my doc gave me this cream for my acne scars and then my face is red…and I have peeling…she said it is normal…to have peeling but do you think I should continue even with the irritation and redness? Is it harmful? It is like a thin layer on my skin…is it supposed to be that way? I apply it every night before retiring….


AskDocWeb: The irritation and redness are common during the first few weeks of use until your skin becomes accustomed to Retin A. That does take a few weeks to happen. As long as you aren’t applying too much, the irritation and redness should be gone by the 8th week.

Subj: Still get the occasional pimple
Date: 1/5/2010
I’ve used Tretinoin for about two months now, and I still get the occasional pimple. Is that normal? I thought it was supposed to stop acne from forming?


AskDocWeb: Tretinoin is a treatment for acne but it is not a cure. If the underlying condition that caused the acne persists then it may produce an occasional pimple but that is less likely to happen if you continue use this medication.

Subj: Difference between Retin-A Micro gel and generic tretinoin gel?
Date: 1/5/2010
Is there a difference between Retin-A Micro gel and generic tretinoin gel? Does the generic still have the slow release microspheres? Fyi to all – Renova and Hydroquine have turned my skin back around and I am now on tretinoin only with great results. After three months All of my melasma is basically gone (caused by a generic does of Birth control pills and sun). It came on suddenly that month! I have since just abandoned all birth control pills for skin, pmdd and clearer skin. I know that tretinoin or the name brands of are golden and work. You do have to be absolutely commited to the instructions and wear sunscreen during the day or block! I no longer need pro activ solution but did love it. If Retin A is not for you that’s my next suggestion. You don’t need both and you’ll just irritate your skin too much. I will actually spend less overtime with tretinoin products than ordering the three step proactiv. I am 36 so for us mature young women retin-a or tretinoin is the way to go!


AskDocWeb: Generic drugs must provide the same therapeutic effect as the brand name drug but make sure it really is a generic and not a brand equivalent, which allows some difference in bioavailability. Some doctors have complained that this difference can be up to plus or minus 20%. Generic tretinoin gel may or may not contain microspheres. In order to get the microspheres, make sure the product name is Tretinoin Microsphere Gel.

Subj: Pigmentation on cheeks
Date: 1/5/2010
Hi, I’m 26yrs and have small pigmentation on my cheeks bones both sides and acne on my chin, I have been using Retino-A few days back… Just wanted to confirm wether will it help reduce both. Thanks,


AskDocWeb: Retin A has been found to be helpful with some pigmentation problems. It reduces or eliminates liver spots, brown spots and some gray growths.

Subj: Treat stretch marks?
Date: 1/6/2010
Hi, I was wondering if it is safe to use retin a micro on the breast to treat stretch marks?


AskDocWeb: Using Retin-A on stretch marks would be an off-label use and is not recommended. It is approved for use only on the face. For stretch marks, there are good reports about a product called Mederma.

Subj: Gum disease and Retin-A
Date: 1/11/2010
I am using a retina A product. Is there any associating with gum deasease? My gums seem to have started bleeding alot since I have been using it on my face.


AskDocWeb: We haven’t found any links between acne and gum disease but there is a growing body of research that links gum disease with cardiovascular disease, stroke, cancer, and some pregnancy complications such as gestational diabetes, pre-mature births, and low birth weight babies.

Subj: Give it time read the directions
Date: 1/15/2010
okay, not trying to be mean but… To use retin a in it’s purest form is the next best thing to botox and fillers probably better!!!!!!! YOU MUST READ AND FOLLOW THE DIRECTIONS TO THE T. U have to or else bad things happen. It’s that bloody powerful. I love it but I am pregnant and it’s advised to stay away from it. You should not use any other acne fighter along with the V-A. Cleanse with a mild creamy cleanser use and SPF of 30 daily. You may need a second moisturizer for the first three months for the day and you may have to alternate nights untill the skin adjusts. IT takes about three months then after that ageless beauty for life because your skin never resists it after long periods of time. Stabelized V-C works well with it. Signature club a does V-C like no other. You will need a separate eye cream. Can anyone tell me what eye creams really targets fine lines? please. Give it time read the directions accordingly and dont tan in the beds. PS I have blackhead acne in the speckled form and it wiped them right out no toner needed!! My retin a is from the obaji line call skincare RX and a trained skincare professional is there to help you.


Subj: Wondering when will my skin improve
Date: 1/15/2010
I have mild acne, mostly whiteheads, clogged pores, scarring, uneven texture, large pores and very oily skin. I have been using tretinon 0.025% cream for 3 weeks, 30mins or longer at bedtime. I skin hasn’t been peeling or burning; I experience no side effects, the only thing that changed is that I’m breaking out alot, bumps, whiteheads and big pimples. Also my pores are 10x bigger and I’m more oily. I don’t know if it is working but I’m getting discouraged. I’m wondering when will my skin improve, I’m scared that I’m going to break out and never stop breaking out or my skin will not improve while on trentinoin. I have a prescription for retin a 0.05%, do you think it will work better? If it does make me peel and scaley, when will it stop? How long should I wait for results? I also used the 0.025% on my back and it has gotten worse than before, my back aches and it feels tender. What am I doing wrong? I’m really frustrated because I feel like there’s a black cloud over my head and I want to hide until my skin gets better but I don’t know when that will happen.


AskDocWeb: Tretinoin is the generic name for Renova. According to the patient information for Renova, for the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. It does not mean that you are doing anything wrong. If you read the patient information you may get a better understanding of what to expect and avoid a lot of frustration. Your skin is likely to start showing improvements after the third week.

Subj: I’m very satisfied
Date: 1/16/2010
I’m a male and currently on my 4th week of RetinA – Tretinoin .025%. I’m very satisfied. My overall skin tone has improved ( I look healthier ) and I my pores have shrunk giving me a smoother surface. But perhaps my favorite surprise is that it’s made shaving MUCH easier. Before, I would almost knick my skin … very sensitive to a blade. However, now the razor glides over my beard with zero cuts and I have a much closer shave! My second week was a bit worrisome in that my face started peeling and not looking too good but after another 5 or so days the peeling stopped and I began to finally notice a difference. I’m 45 years old and I think I’m noticing that some small wrinkles are less noticeable. But again, I think the main improvement is in my even skin tone which in turn helps hide those flaws perhaps. I recommend the treatment.


Subj: Atralin?
Date: 1/18/2010
I was on accutane and once I completed the 5 month process my doctor put me on Retin A. I cant afford to buy the prescription for Retin A. But Atralin is alot cheaper. What is the big difference? Is it ok to go from Retin A to Atralin? Thanks,


AskDocWeb: Atralin is just one of the brand names of the generic drug tretinoin (TRET in oin). Other brand names include Altinac, Avita, Renova, Retin A Micro Gel, Retin-A, and Tretin-X.

Subj: Tetracycline and Retin-A
Date: 1/18/2010
I am going to be taking Tetracycline and Retin-A. Wouldn’t my dermatologist recognize this as an unlikely combination? Why did he prescribe them both?


AskDocWeb: Acne is often treated with a combination of oral antibiotics and Retin-A, including tetracycline. Although there is a possibility of serious adverse reactions, these events are rare (see The Journal of Family Practice, April 2004).

Subj: Dark gray skin
Date: 1/19/2010
I have used Retin-A cream for about two years now, starting with a .010% cream and building up to a .05% cream. I have a lot of seasonal allergies and so blow my nose a lot. What I have seen develop is a dark gray skin over my upper lip. Yech! It looks like a mustache! I am horrified. What has caused this? I wear sunscreen every day and have wondered if I rub off the sunscreen when I blow my nose and so that part of my face is just more exposed to darkening. Is that it? or is it something else? Any ideas of how to get rid of it?


AskDocWeb: It’s easy to see how blowing your nose could wipe off the sunscreen and although it is rare, the sun is known to sometimes cause the skin to turn dark gray. Protecting that area from the sun would at least prevent it from getting worse. Other than replacing the sunscreen you would have to ask a dermatologist for other ideas about what to do about it.

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